Pathology and Cell Biology
USF Health - College of Medicine
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Karl Muffly , Ph.D.

Primary Department: COLLEGE OF MEDICINE PATHOLOGY & CELL BIOLOGY

Assoc Professor
COLLEGE OF MEDICINE SURGERY

Associate Professor
COLLEGE OF MEDICINE PATHOLOGY & CELL BIOLOGY
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Contacts
Email: kmuffly@health.usf.edu
Phone: (813) 974-9385
Office: MDC, 2008
Mailing address 12901 Bruce B. Downs Blvd. ,MDC 11
Tampa, FL 33612
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Education
  • PHD, Anatomy, University Of Nebraska , Omaha, United States - 1984.
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  • M.S., Anatomy, University of Nebraska Medical Center ,USA - 1982.
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  • B.S., Zoology, University of Nebraska ,USA - 1978.
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    Interdisciplinary & Emerging Signature Programs
    Cardiovascular, Biomedical Engineering & Nanomedicine.
     
    Research Summary

    Role and characterization of cytoskeletol elements in cellular structure and function

    Role and effects of steroid hormones on cardiac hypertrophy and failure

    Characterization of cardiac muscle and valvular tissue

    Histogenesis in humans

    Development of digital resources for science education

    Use of in vitro models in bioengineering
     


    Selected Publications
  • Cameron, DF.Muffly, KE.Nazian, SJ. Development of Sertoli cell binding competency in the peripubertal rat. Journal of andrology. 19(5): 573-9, .
  • Muffly, KE.McWhorter, CA.Bartone, FF.Gardner, PJ. The absence of premalignant changes in the cryptorchid testis before adulthood. The Journal of urology. 131(3): 523-5, 1984.
  • Muffly, KE.Turner, TT.Brown, M.Hall, PF. Content of K+ and Na+ in seminiferous tubule and rete testis fluids from Sertoli cell-enriched testes. Biology of reproduction. 33(5): 1245-51, 1985.
  • Kew, D.Muffly, KE.Hall, PF. Plasma membranes from rat Sertoli cells: purification and properties. Biology of reproduction. 35(5): 1235-47, 1986.
  • Borland, K.Muffly, KE.Hall, PF. Production of components of extracellular matrix by cultured rat Sertoli cells. Biology of reproduction. 35(4): 997-1008, 1986.
  • della-Cioppa, G.Muffly, KE.Yanagibashi, K.Hall, PF. Preparation and characterization of submitochondrial fractions from adrenal cells. Molecular and cellular endocrinology. 48(2-3): 111-20, 1986.
  • Ehrlich, HP.Borland, KM.Muffly, KE.Hall, PF. Contraction of collagen lattice by peritubular cells from rat testis. Journal of cell science. 82(): 281-94, 1986.
  • Jin, DF.Muffly, KE.Okulicz, WC.Kilpatrick, DL. Estrous cycle- and pregnancy-related differences in expression of the proenkephalin and proopiomelanocortin genes in the ovary and uterus. Endocrinology. 122(4): 1466-71, 1988.
  • Muffly, KE.Jin, DF.Okulicz, WC.Kilpatrick, DL. Gonadal steroids regulate proenkephalin gene expression in a tissue-specific manner within the female reproductive system. Molecular endocrinology (Baltimore, Md.). 2(10): 979-85, 1988.
  • Muffly, KE.Hall, PF. Vectorial (transcellular) transport of potassium (86Rb+) by cultured Sertoli cells. Endocrinology. 123(4): 2083-8, 1988.
  • Kew, D.Muffly, KE.Kilpatrick, DL. Proenkephalin products are stored in the sperm acrosome and may function in fertilization. Proceedings of the National Academy of Sciences of the United States of America. 87(23): 9143-7, 1990.
  • Cameron, DF.Muffly, KE. Hormonal regulation of spermatid binding. Journal of cell science. 100 ( Pt 3)(): 623-33, 1991.
  • Gerdes, AM.Kellerman, SE.Moore, JA.Muffly, KE.Clark, LC.Reaves, PY.Malec, KB.McKeown, PP.Schocken, DD. Structural remodeling of cardiac myocytes in patients with ischemic cardiomyopathy. Circulation. 86(2): 426-30, 1992.
  • Cameron, DF.Muffly, KE.Nazian, SJ. Reduced testosterone during puberty results in a midspermiogenic lesion. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 202(4): 457-64, 1993.
  • Muffly, KE.Nazian, SJ.Cameron, DF. Junction-related Sertoli cell cytoskeleton in testosterone-treated hypophysectomized rats. Biology of reproduction. 49(5): 1122-32, 1993.
  • Nazian, SJ.Landon, CS.Muffly, KE.Cameron, DF. Opioid inhibition of adrenergic and dopaminergic but not serotonergic stimulation of luteinizing hormone releasing hormone release from immortalized hypothalamic neurons. Molecular and cellular neurosciences. 5(6): 642-8, 1994.
  • Muffly, KE.Nazian, SJ.Cameron, DF. Effects of follicle-stimulating hormone on the junction-related Sertoli cell cytoskeleton and daily sperm production in testosterone-treated hypophysectomized rats. Biology of reproduction. 51(1): 158-66, 1994.
  • Cameron, DF.Muffly, KE.Travis, DT.McNeely, HA. Training with cadavers. A class act. JEMS : a journal of emergency medical services. 20(6): 51-7, 59-60, 1995.
  • Yamaguchi, H.Haranaga, S.Friedman, H.Moor, JA.Muffly, KE.Yamamoto, Y. A Chlamydia pneumoniae infection model using established human lymphocyte cell lines. FEMS microbiology letters. 216(2): 229-34, 2002.
  • Knight, J.Kurtcuoglu, V.Muffly, K.Marshall, W.Stolzmann, P.Desbiolles, L.Seifert, B.Poulikakos, D.Alkadhi, H. Ex vivo and in vivo coronary ostial locations in humans. Surgical and radiologic anatomy : SRA. 31(8): 597-604, 2009.

    • Positions Held
  • Associate Professor (Co-Appointment) (Department of Surgery, College of Medicine, University of South Florida 1995 - Present)
  • Associate Professor (Dept. of Pathology and Cell Biology, College of Medicine, University of South Florida 1994 - Present)
  • Assisstant Professor (Department of Anatomy, College of Medicine, University of South Florida 1988 - 1994)


    • Memberships
  • American Association of Anatomists (Member, 2008 - Present)
  • Society for the Study of Reproduction (Member, 2008 - Present)
  • American Society of Andrology (Member, 2008 - Present)
  • American Association of the Advancement of Science (Member, 2008 - Present)
  • Florida Society of Electron Microscopy (President-elect, 1998)(President, 1999) (Member, 2008 - Present)


    • Awards/Honors
  • Oustanding Basic Science Instructor Class 2008 (University of South Florida - College of Medicine - 2008)
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  • Outstanding Freshman Instructor Class 2009 (University of South Florida - College of Medicine - 2007)
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  • Basic Science Graduation Ceremony Hooder Class 2007 (University of South Florida, College of Medicine - 2007)
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  • Nominated for AAMS/Pfizer humanism in medicine award (USF-COM One nominee is picked from each Medical school for this national award - 2006)
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    Profile last modified on 10/03/2008