Molecular Pharmacology and Physiology
USF Health � College of Medicine
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Alison Willing , PHD

Primary Department: CENTER OF EXCELLENCE FOR AGING & BRAIN REPAIR

Professor
CENTER OF EXCELLENCE FOR AGING & BRAIN REPAIR

Professor
COLLEGE OF MEDICINE MOLECULAR PHARMACOLOGY & PHYSIOLOGY

Professor
COLLEGE OF MEDICINE PATHOLOGY & CELL BIOLOGY
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Contacts
Email: awilling@health.usf.edu
Phone: (813) 974-7812
Office: MDT, 1581
Mailing address 12901 Bruce B. Downs Blvd ,MDC78
Tampa, FL 33612
 
Education
  • PHD, Medical Physiology, University Of Calgary , Canada - 1993.
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  • MA, Psychology, University of Calgary ,USA - 1990.
    		•
     
    Interdisciplinary & Emerging Signature Programs
    Neuroscience.
     


    Selected Publications
  • Garbuzova-Davis, S.Willing, AE.Saporta, S.Bickford, PC.Gemma, C.Chen, N.Sanberg, CD.Klasko, SK.Borlongan, CV.Sanberg, PR. Novel cell therapy approaches for brain repair. Progress in brain research. 157(): 207-22, 2006.
  • Garbuzova-Davis, S.Willing, AE.Saporta, S.Justen, EB.Misiuta, IE.Dellis, J.Sanberg, PR. Multiple transplants of hNT cells into the spinal cord of SOD1 mouse model of familial amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. 7(4): 221-6, 2006.
  • Shamekh, R.Cameron, DF.Willing, AE.Saporta, S. The role of connexins in the differentiation of NT2 cells in Sertoli-NT2 cell tissue constructs grown in the rotating wall bioreactor. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. 170(2): 277-84, 2006.
  • Walczak, P.Chen, N.Eve, D.Hudson, J.Zigova, T.Sanchez-Ramos, J.Sanberg, PR.Sanberg, CD.Willing, AE. Long-term cultured human umbilical cord neural-like cells transplanted into the striatum of NOD SCID mice. Brain research bulletin. 74(1-3): 155-63, 2007.
  • Willing, AE.Pennypacker, KR. Alternate approach to understanding the molecular mechanisms of stroke-induced injury. Histology and histopathology. 22(6): 697-701, 2007.
  • Chen, N.Kamath, S.Newcomb, J.Hudson, J.Garbuzova-Davis, S.Bickford, P.Davis-Sanberg, C.Sanberg, P.Zigova, T.Willing, A. Trophic factor induction of human umbilical cord blood cells in vitro and in vivo. Journal of neural engineering. 4(2): 130-45, 2007.
  • Newcomb, JD.Sanberg, PR.Klasko, SK.Willing, AE. Umbilical cord blood research: current and future perspectives. Cell transplantation. 16(2): 151-8, 2007.
  • Newcomb, JD.Janowski, M.Zigova, T.Saporta, S.McGrogan, MP.Sanberg, PR.Willing, AE. A comparison of dopaminergic cells from the human NTera2/D1 cell line transplanted into the hemiparkinsonian rat. Life Sciences. 81(6): 441-448, 2007.
  • Willing, AE.Eve, DJ.Sanberg, PR. Umbilical cord blood transfusions for prevention of progressive brain injury and induction of neural recovery: an immunological perspective. Regenerative medicine. 2(4): 457-64, 2007.
  • Bachstetter, AD.Pabon, MM.Cole, MJ.Hudson, CE.Sanberg, PR.Willing, AE.Bickford, PC.Gemma, C. Peripheral injection of human umbilical cord blood stimulates neurogenesis in the aged rat brain. BMC neuroscience. 9(): 22, 2008.
  • Ajmo, CT.Vernon, DO.Collier, L.Hall, AA.Garbuzova-Davis, S.Willing, A.Pennypacker, KR. The spleen contributes to stroke-induced neurodegeneration. Journal of neuroscience research. 86(10): 2227-34, 2008.
  • Ajmo, CT.Collier, LA.Leonardo, CC.Hall, AA.Green, SM.Womble, TA.Cuevas, J.Willing, AE.Pennypacker, KR. Blockade of adrenoreceptors inhibits the splenic response to stroke. Experimental neurology. 218(1): 47-55, 2009.
  • Leonardo, CC.Hall, AA.Collier, LA.Ajmo, CT.Willing, AE.Pennypacker, KR. Human umbilical cord blood cell therapy blocks the morphological change and recruitment of CD11b-expressing, isolectin-binding proinflammatory cells after middle cerebral artery occlusion. Journal of neuroscience research. 88(6): 1213-22, 2010.
  • Leonardo, CC.Hall, AA.Collier, LA.Green, SM.Willing, AE.Pennypacker, KR. Administration of a Sigma Receptor Agonist Delays MCAO-Induced Neurodegeneration and White Matter Injury. Translational stroke research. 1(2): 135-145, 2010.
  • Jiang, L.Saporta, S.Chen, N.Sanberg, CD.Sanberg, P.Willing, A. The effect of human umbilical cord blood cells on survival and cytokine production by post-ischemic astrocytes in vitro. Stem cell reviews. 6(4): 523-31, 2010.
  • Chen, N.Newcomb, J.Garbuzova-Davis, S.Davis Sanberg, C.Sanberg, PR.Willing, AE. Human Umbilical Cord Blood Cells Have Trophic Effects on Young and Aging Hippocampal Neurons in Vitro. Aging and disease. 1(3): 173-190, 2010.

    • Memberships
  • AAAS (Fellow, 2012 - Present)
  • American Society for Neural Therapy & Repair ( Councillor, 1997 - Present)
  • Cell Transplant Society ( , 1997 - Present)
  • International Behavioral Neuroscience Society ( , 1995 - Present)
  • Society for Neuroscience ( , 1994 - Present)


    • Grants
  • CORD BLOOD IS NEUROPROTECTIVE IN A RAT MODEL OF STROKE ($85,272.00, 03/01/2006-02/28/2011)
  • CORD BLOOD IS NEUROPROTECTIVE IN A RAT MODEL OF STROKE ($308,176.00, 03/01/2006-02/28/2011)
  • CORD BLOOD IS NEUROPROTECTIVE IN A RAT MODEL OF STROKE ($311,289.00, 03/01/2006-02/28/2011)
  • CORD BLOOD IS NEUROPROTECTIVE IN A RAT MODEL OF STROKE ($392,488.00, 03/01/2006-02/28/2011)
  • CORD BLOOD IS NEUROPROTECTIVE IN A RAT MODEL OF STROKE ($92,625.00, 03/01/2006-02/28/2011)
  • CORD BLOOD IS NEUROPROTECTIVE IN A RAT MODEL OF STROKE ($311,289.00, 03/01/2006-02/28/2011)
  • CORD BLOOD IS NEUROPROTECTIVE IN A RAT MODEL OF STROKE ($320,586.00, 03/01/2006-02/28/2011)
  • SPLENIC MECHANISMS OF CORD BLOOD INDUCED BRAIN REPAIR ($200,000.00, 07/01/2007-12/31/2008)
  • TROPHIC EFFECTS OF CORD BLOOD IN AGING BRAIN ($80,000.00, 10/01/2007-09/30/2008)
  • POTENTIAL OF CORD BLOOD CELLS TO RESCUE AGING BRAIN ($247,786.00, 05/01/2002-04/30/2008)
  • ANTI-INFLAMMATORY THERAPY FOR STROKE, INDUCED WITH ALLOGENEIC OR XENOGENEIC CORD BLOOD CELLS ($60,000.00, 07/01/2005-06/30/2007)
  • ANTI-INFLAMMATORY THERAPY FOR STROKE, INDUCED WITH ALLOGENEIC OR XENOGENEIC CORD BLOOD CELLS ($60,000.00, 07/01/2005-06/30/2007)
  • POTENTIAL OF CORD BLOOD CELLS TO RESCUE AGING BRAIN ($253,750.00, 05/01/2002-04/30/2007)
  • POTENTIAL OF CORD BLOOD CELLS TO RESCUE AGING BRAIN ($253,750.00, 05/01/2002-04/30/2007)
  • POTENTIAL OF CORD BLOOD CELLS TO RESCUE AGING BRAIN ($277,603.00, 05/01/2002-04/30/2007)
  • MODULATION OF STROKE-INDUCED INFLAMMATORY RESPONSES IN RATS WITH INTRAVENOUS DELIVERY OF HUMAN UMBILICAL CORD BLOOD CELLS ($60,000.00, 07/01/2003-06/30/2005)
  • MODULATION OF STROKE-INDUCED INFLAMMATORY RESPONSES IN RAT WITH INTRAVENOUS DELIVERY OF HUMAN UMBILICAL CORD BLOOD CELLS ($60,000.00, 07/01/2003-06/30/2005)
  • TRANSPLANTATION OF UMBILICAL CORD BLOOD MINIMIZES INJURY AFTER STROKE ($155,011.00, 06/01/2001-06/30/2004)
  • LENTIVIRAL VECTOR APPROACH FOR LABELING STEM CELLS ($20,000.00, 06/16/2003-06/15/2004)
  • POTENTIAL OF CORD BLOOD CELLS TO RESCUE AGING BRAIN ($253,750.00, 05/01/2002-04/30/2004)
  • SERTOLI CELL CO-TRANSPLANTS IN PARKINSON'S DISEASE ($70,000.00, 08/15/2001-07/31/2002)
  • TRANSPLANTATION OF UMBILICAL CORD MINIMIZES INJURY AFTER STROKE ($200,000.00, 06/01/2001-06/30/2002)
  • LITHIUM INCREASES DOPAMINERGIC PHENOTYPE IN HNT NEURONS ($60,000.00, 08/04/2000-12/31/2001)
  • NEUROGENESIS IN THE ADULT BRAIN AFTER STROKE ($7,000.00, 07/01/2000-12/31/2001)
  • NEURAL TRANSPLANTATION OF HUMAN POST-MYOTIC CNS CELL LINE ($143,400.00, 01/01/2000-12/31/2001)
  • IN VIVO GRAFTING STUDIES OF THE EMBRYONIC STEM CELLS AND BONE MARROW STROMAL CELLS ($25,200.00, 08/01/1999-07/31/2000)


    • Profile last modified on 01/28/2013