Pathology and Cell Biology
USF Health - College of Medicine
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Samuel Saporta , Ph.D.

Primary Department: COLLEGE OF MEDICINE PATHOLOGY & CELL BIOLOGY
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Contacts
Email: ssaporta@health.usf.edu
Phone: (813) 974-9445
Office: MDC, 2539
Mailing address 12901 Bruce B. Downs Blvd. ,MDC 11
Tampa, FL 33612
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Education
  • PHD, Neurobiology/Experimental Psychology, University Of Southern California , Los Angeles, United States - 1973.
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  • B.A., Psychology/Neurobiology, University of California ,USA - 1967.
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    Interdisciplinary & Emerging Signature Programs
    Neuroscience.
     


    Selected Publications
  • Greene, E.Saporta, S.Walters, J. Choice bias from unilateral hippocampal or frontal lesions in the rat. Experimental neurology. 29(3): 534-545, 1970.
  • Saporta, S.Greene, E. Orienting bias in the rat produced by hippocampal lesion. Behavioral biology. 11(3): 339-51, 1974.
  • Furstman, L.Saporta, S.Kruger, L. Retrograde axonal transport of horseradish peroxidase in sensory nerves and ganglion cells of the rat. Brain research. 84(2): 320-4, 1975.
  • Saporta, S.Kruger, L. The organization of thalamocortical relay neurons in the rat ventrobasal complex studied by the retrograde transport of horseradish peroxidase. The Journal of comparative neurology. 174(2): 187-208, 1977.
  • Kruger, L.Saporta, S. Axonal transport of [3H]adenosine in visual and somatosensory pathways. Brain research. 122(1): 132-6, 1977.
  • Saporta, S.Kruger, L. The organization of projections to selected points of somatosensory cortex from the cat ventrobasal complex. Brain research. 178(2-3): 275-95, 1979.
  • Phelps, CP.Nance, DM.Saporta, S. Reduced ovarian function and lordosis behavior following hypothalamic knife cuts. Brain research bulletin. 5(5): 531-537, 1980.
  • Colombo, JA.Saporta, S. Increased local uptake of 2-deoxyglucose after electrochemical or direct deposition of iron into the rat brain. Experimental neurology. 70(2): 427-37, 1980.
  • Nance, DM.Saporta, S.Phelps, CP. Effects of hypothalamic knife cuts on estrogenic control of feeding behavior. Brain research bulletin. 6(3): 259-66, 1981.
  • Saporta, S.Phelps, CP.Nance, DM. Neural damage following retrochiasmatic knife cuts in the rat. Brain research bulletin. 7(3): 267-78, 1981.
  • Golovchinsky, V.Kruger, L.Saporta, SA.Stein, BE.Young, DW. Properties of velocity-mechanosensitive neurons of the cat ventrobasal thalamic nucleus with special reference to the concept of convergence. Brain research. 209(2): 355-74, 1981.
  • Saporta, S.Eichler, DC. Conjugated dimers of horseradish peroxidase as neuroanatomical tracers. Brain research. 250(1): 149-53, 1982.
  • Shannon, R.Saporta, S.Lindsey, BG. Transmission of intercostal muscle proprioceptor afferent information to medullary respiratory areas. Experimental neurology. 78(1): 222-5, 1982.
  • Phelps, CP.Saporta, S. Electrochemical stimulation of plasma LH and hypothalamic norepinephrine concentrations at short- and long-term intervals after hypothalamic knife cuts. Brain research. 347(2): 328-35, 1985.
  • Colombo, JA.Ritterman, SI.Saporta, S. Neural projections of the preoptic-suprachiasmatic region to the median eminence in the rat: a quantitative autoradiographic study. Experimental neurology. 90(3): 510-21, 1985.
  • Saporta, S.Phelps, CP. Long-term reorganization of afferents to the mediobasal hypothalamus following retrochiasmatic knife cuts. A study using horseradish peroxidase. Brain research. 347(2): 336-45, 1985.
  • Saporta, S. Loss of spinothalamic tract neurons following neonatal treatment of rats with the neurotoxin capsaicin. Somatosensory research. 4(2): 153-73, 1986.
  • Segers, LS.Shannon, R.Saporta, S.Lindsey, BG. Functional associations among simultaneously monitored lateral medullary respiratory neurons in the cat. I. Evidence for excitatory and inhibitory actions of inspiratory neurons. Journal of neurophysiology. 57(4): 1078-100, 1987.
  • Phelps, CP.Saporta, S. The release of pituitary LH and sprouting of LH-releasing hormone (LHRH)-containing neurons after anterior hypothalamic deafferentation. Brain research. 454(1-2): 188-204, 1988.
  • Saporta, S.Henderson, CN. Enhancement of horseradish peroxidase histochemistry and/or uptake with radiocontrast media. Journal of neuroscience methods. 37(3): 233-40, 1991.
  • Saporta, S. How plastic is the central nervous system? The Journal of the Florida Medical Association. 79(9): 645-7, 1992.
  • Wiranowska, M.Gonzalvo, AA.Saporta, S.Gonzalez, OR.Prockop, LD. Evaluation of blood-brain barrier permeability and the effect of interferon in mouse glioma model. Journal of neuro-oncology. 14(3): 225-36, 1992.
  • Wiranowska, M.Prockop, LD.Naidu, AK.Saporta, S.Kori, S.Kulkarni, AP. Interferon entry through the blood-brain barrier in glioma and its effect on lipoxygenase activity. Anticancer research. 14(3A): 1121-1126, 1994.
  • Lindsey, BG.Segers, LS.Morris, KF.Hernandez, YM.Saporta, S.Shannon, R. Distributed actions and dynamic associations in respiratory-related neuronal assemblies of the ventrolateral medulla and brain stem midline: evidence from spike train analysis. Journal of neurophysiology. 72(4): 1830-51, 1994.
  • Borlongan, CV.Stahl, CE.Cameron, DF.Saporta, S.Freeman, TB.Cahill, DW.Sanberg, PR. CNS immunological modulation of neural graft rejection and survival. Neurological research. 18(4): 297-304, 1996.
  • Sanberg, PR.Borlongan, CV.Saporta, S.Cameron, DF. Testis-derived Sertoli cells survive and provide localized immunoprotection for xenografts in rat brain. Nature biotechnology. 14(13): 1692-5, 1996.
  • Saporta, S.Cameron, DF.Borlongan, CV.Sanberg, PR. Survival of rat and porcine Sertoli cell transplants in the rat striatum without cyclosporine-A immunosuppression. Experimental neurology. 146(2): 299-304, 1997.
  • Sanberg, PR.Othberg, AI.Borlongan, CV.Saporta, S.Anton, A.Freeman, TB.Cahill, DW.Allen, RC.Cameron, DF. Transplantation of testis-derived Sertoli cells into the mammalian brain. Transplantation proceedings. 29(4): 1926-8, 1997.
  • Sanberg, PR.Borlongan, CV.Othberg, AI.Saporta, S.Freeman, TB.Cameron, DF. Testis-derived Sertoli cells have a trophic effect on dopamine neurons and alleviate hemiparkinsonism in rats. Nature medicine. 3(10): 1129-32, 1997.
  • Sanberg, PR.Saporta, S.Borlongan, CV.Othberg, AI.Allen, RC.Cameron, DF. The testis-derived cultured Sertoli cell as a natural Fas-L secreting cell for immunosuppressive cellular therapy. Cell transplantation. 6(2): 191-193, 1997.
  • Cameron, DF.Othberg, AI.Borlongan, CV.Rashed, S.Anton, A.Saporta, S.Sanberg, PR. Post-thaw viability and functionality of cryopreserved rat fetal brain cells cocultured with Sertoli cells. Cell transplantation. 6(2): 185-189, 1997.
  • Saporta, S.Borlongan, C.Moore, J.Mejia-Millan, E.Jones, SL.Bonness, P.Randall, TS.Allen, RC.Freeman, TB.Sanberg, PR. Microcarrier enhanced survival of human and rat fetal ventral mesencephalon cells implanted in the rat striatum. Cell transplantation. 6(6): 579-84, 1997.
  • Borlongan, CV.Cameron, DF.Saporta, S.Sanberg, PR. Intracerebral transplantation of testis-derived sertoli cells promotes functional recovery in female rats with 6-hydroxydopamine-induced hemiparkinsonism. Experimental neurology. 148(1): 388-92, 1997.
  • Borlongan, CV.Koutouzis, TK.Poulos, SG.Saporta, S.Sanberg, PR. Bilateral fetal striatal grafts in the 3-nitropropionic acid-induced hypoactive model of Huntington's disease. Cell transplantation. 7(2): 131-5, 1998.
  • Wiranowska, M.Tresser, N.Saporta, S. The effect of interferon and anti-CD44 antibody on mouse glioma invasiveness in vitro. Anticancer research. 18(5A): 3331-8, 1998.
  • Borlongan, CV.Saporta, S.Poulos, SG.Othberg, A.Sanberg, PR. Viability and survival of hNT neurons determine degree of functional recovery in grafted ischemic rats. Neuroreport. 9(12): 2837-42, 1998.
  • Othberg, AI.Willing, AE.Saporta, S.Cameron, DF.Sanberg, PR. Preparation of cell suspensions for co-transplantation: methodological considerations. Neuroscience letters. 247(2-3): 111-4, 1998.
  • Borlongan, CV.Saporta, S.Sanberg, PR. Intrastriatal transplantation of rat adrenal chromaffin cells seeded on microcarrier beads promote long-term functional recovery in hemiparkinsonian rats. Experimental neurology. 151(2): 203-14, 1998.
  • Othberg, AI.Willing, AE.Cameron, DF.Anton, A.Saporta, S.Freeman, TB.Sanberg, PR. Trophic effect of porcine Sertoli cells on rat and human ventral mesencephalic cells and hNT neurons in vitro. Cell transplantation. 7(2): 157-64, 1998.
  • Saporta, S.Borlongan, CV.Sanberg, PR. Neural transplantation of human neuroteratocarcinoma (hNT) neurons into ischemic rats. A quantitative dose-response analysis of cell survival and behavioral recovery. Neuroscience. 91(2): 519-25, 1999.
  • Zigova, T.Willing, AE.Tedesco, EM.Borlongan, CV.Saporta, S.Snable, GL.Sanberg, PR. Lithium chloride induces the expression of tyrosine hydroxylase in hNT neurons. Experimental neurology. 157(2): 251-8, 1999.
  • Willing, AE.Sudberry, JJ.Othberg, AI.Saporta, S.Poulos, SG.Cameron, DF.Freeman, TB.Sanberg, PR. Sertoli cells decrease microglial response and increase engraftment of human hNT neurons in the hemiparkinsonian rat striatum. Brain research bulletin. 48(4): 441-4, 1999.
  • Willing, AE.Othberg, AI.Saporta, S.Anton, A.Sinibaldi, S.Poulos, SG.Cameron, DF.Freeman, TB.Sanberg, PR. Sertoli cells enhance the survival of co-transplanted dopamine neurons. Brain research. 822(1-2): 246-50, 1999.
  • Sanchez-Ramos, J.Song, S.Cardozo-Pelaez, F.Hazzi, C.Stedeford, T.Willing, A.Freeman, TB.Saporta, S.Janssen, W.Patel, N.Cooper, DR.Sanberg, PR. Adult bone marrow stromal cells differentiate into neural cells in vitro. Experimental neurology. 164(2): 247-56, 2000.
  • Wiranowska, M.Rojiani, AM.Gottschall, PE.Moscinski, LC.Johnson, J.Saporta, S. CD44 expression and MMP-2 secretion by mouse glioma cells: effect of interferon and anti-CD44 antibody. Anticancer research. 20(6B): 4301-4306, 2000.
  • Freeman, TB.Cicchetti, F.Hauser, RA.Deacon, TW.Li, XJ.Hersch, SM.Nauert, GM.Sanberg, PR.Kordower, JH.Saporta, S.Isacson, O. Transplanted fetal striatum in Huntington's disease: phenotypic development and lack of pathology. Proceedings of the National Academy of Sciences of the United States of America. 97(25): 13877-82, 2000.
  • Saporta, S.Willing, AE.Colina, LO.Zigova, T.Milliken, M.Daadi, MM.Sanberg, PR. In vitro and in vivo characterization of hNT neuron neurotransmitter phenotypes. Brain research bulletin. 53(3): 263-8, 2000.
  • Freeman, TB.Hauser, RA.Willing, AE.Zigova, T.Sanberg, PR.Saporta, S. Transplantation of human fetal striatal tissue in Huntington's disease: rationale for clinical studies. Novartis Foundation symposium. 231(): 129-38; discussion 139-47, 2000.
  • Freeman, TB.Hauser, RA.Sanberg, PR.Saporta, S. Neural transplantation for the treatment of Huntington's disease. Progress in brain research. 127(): 405-11, 2000.
  • Sanchez-Ramos, J.Song, S.Dailey, M.Cardozo-Pelaez, F.Hazzi, C.Stedeford, T.Willing, A.Freeman, TB.Saporta, S.Zigova, T.Sanberg, PR.Snyder, EY. The X-gal caution in neural transplantation studies. Cell transplantation. 9(5): 657-67, 2000.
  • Zigova, T.Barroso, LF.Willing, AE.Saporta, S.McGrogan, MP.Freeman, TB.Sanberg, PR. Dopaminergic phenotype of hNT cells in vitro. Brain research. Developmental brain research. 122(1): 87-90, 2000.
  • Cameron, DF.Hushen, JJ.Nazian, SJ.Willing, A.Saporta, S.Sanberg, PR. Formation of Sertoli cell-enriched tissue constructs utilizing simulated microgravity technology. Annals of the New York Academy of Sciences. 944(): 420-8, 2001.
  • Saporta, S.Willing, AE.Zigova, T.Daadi, MM.Sanberg, PR. Comparison of calcium-binding proteins expressed in cultured hNT neurons and hNT neurons transplanted into the rat striatum. Experimental neurology. 167(2): 252-9, 2001.
  • Zigova, T.Willing, AE.Saporta, S.Daadi, MM.McGrogan, MP.Randall, TS.Freeman, TB.Sanchez-Ramos, J.Sanberg, PR. Apoptosis in cultured hNT neurons. Brain research. Developmental brain research. 127(1): 63-70, 2001.
  • Daadi, MM.Saporta, S.Willing, AE.Zigova, T.McGrogan, MP.Sanberg, PR. In vitro induction and in vivo expression of bcl-2 in the hNT neurons. Brain research bulletin. 56(2): 147-52, 2001.
  • Pennypacker, KR.Kassed, CA.Eidizadeh, S.Saporta, S.Sanberg, PR.Willing, AE. NF-kappaB p50 is increased in neurons surviving hippocampal injury. Experimental neurology. 172(2): 307-19, 2001.
  • Willing, AE.Garbuzova-Davis, S.Saporta, S.Milliken, M.Cahill, DW.Sanberg, PR. hNT neurons delay onset of motor deficits in a model of amyotrophic lateral sclerosis. Brain research bulletin. 56(6): 525-30, 2001.
  • Garbuzova-Davis, S.Willing, AE.Milliken, M.Saporta, S.Sowerby, B.Cahill, DW.Sanberg, PR. Intraspinal implantation of hNT neurons into SOD1 mice with apparent motor deficit. Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases. 2(4): 175-80, 2001.
  • Zigova, T.Song, S.Willing, AE.Hudson, JE.Newman, MB.Saporta, S.Sanchez-Ramos, J.Sanberg, PR. Human umbilical cord blood cells express neural antigens after transplantation into the developing rat brain. Cell transplantation. 11(3): 265-74, 2002.
  • Saporta, S.Makoui, AS.Willing, AE.Daadi, M.Cahill, DW.Sanberg, PR. Functional recovery after complete contusion injury to the spinal cord and transplantation of human neuroteratocarcinoma neurons in rats. Journal of neurosurgery. 97(1 Suppl): 63-8, 2002.
  • Cameron, DF.Hushen, JJ.Dejarlais, T.Colado, L.Wolski, KM.Sanberg, PR.Saporta, S. A unique cytoplasmic marker for extratesticular Sertoli cells. Cell transplantation. 11(6): 507-12, 2002.
  • Willing, AE.Zigova, T.Milliken, M.Poulos, S.Saporta, S.McGrogan, M.Snable, G.Sanberg, PR. Lithium exposure enhances survival of NT2N cells (hNT neurons) in the hemiparkinsonian rat. The European journal of neuroscience. 16(12): 2271-8, 2002.
  • Rodríguez, AI.Willing, AE.Cameron, DF.Saporta, S.Sandberg, PR. Neurobehavioral assessment of transplanted porcine Sertoli cells into the intact rat striatum. Neurotoxocology research. 4(2): 103-9, 2002.
  • Willing, AE.Saporta, S.Lixian, J.Milliken, M.Poulos, S.Bowersox, SS.Sanberg, PR. Preliminary study of the behavioral effects of LBS-neuron implantation on seizure susceptibility following middle cerebral artery occlusion in the rats. . 4(2): 111-8, 2002.
  • Willing, AE.Garbuzova-Davis, S.Sanberg, PR.Saporta, S. Routes of stem cell administration in the adult rodent. Methods in molecular biology (Clifton, N.J.). 198(): 357-74, 2002.
  • Garbuzova-Davis, S.Willing, AE.Milliken, M.Saporta, S.Zigova, T.Cahill, DW.Sanberg, PR. Positive effect of transplantation of hNT neurons (NTera 2/D1 cell-line) in a model of familial amyotrophic lateral sclerosis. Experimental neurology. 174(2): 169-80, 2002.
  • Saporta, S.Kim, JJ.Willing, AE.Fu, ES.Davis, CD.Sanberg, PR. Human umbilical cord blood stem cells infusion in spinal cord injury: engraftment and beneficial influence on behavior. Journal of hematotherapy & stem cell research. 12(3): 271-8, 2003.
  • Hazlehurst, LA.Enkemann, SA.Beam, CA.Argilagos, RF.Painter, J.Shain, KH.Saporta, S.Boulware, D.Moscinski, L.Alsina, M.Dalton, WS. Genotypic and phenotypic comparisons of de novo and acquired melphalan resistance in an isogenic multiple myeloma cell line model. Cancer research. 63(22): 7900-6, 2003.
  • Rodriguez, AI.Willing, AE.Saporta, S.Cameron, DF.Sanberg, PR. Effects of Sertoli cell transplants in a 3-nitropropionic acid model of early Huntington's disease: a preliminary study. Neurotoxicity research. 5(6): 443-50, 2003.
  • Garbuzova-Davis, S.Willing, AE.Zigova, T.Saporta, S.Justen, EB.Lane, JC.Hudson, JE.Chen, N.Davis, CD.Sanberg, PR. Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation. Journal of hematotherapy & stem cell research. 12(3): 255-70, 2003.
  • Hudson, JE.Chen, N.Song, S.Walczak, P.Jendelová, P.Sykova, E.Willing, AE.Saporta, S.Bickford, P.Sanchez-Ramos, J.Zigova, T. Green fluorescent protein bone marrow cells express hematopoietic and neural antigens in culture and migrate within the neonatal rat brain. Journal of neuroscience research. 76(2): 255-64, 2004.
  • Saporta, S.Willing, AE.Shamekh, R.Bickford, P.Paredes, D.Cameron, DF. Rapid differentiation of NT2 cells in Sertoli-NT2 cell tissue constructs grown in the rotating wall bioreactor. Brain research bulletin. 64(4): 347-56, 2004.
  • Cameron, DF.Hushen, JJ.Colina, L.Mallery, J.Willing, A.Sanberg, PR.Saporta, S. Formation and structure of transplantable tissue constructs generated in simulated microgravity from Sertoli cells and neuron precursors. Cell transplantation. 13(7-8): 755-63, 2004.
  • Fu, ES.Saporta, S. Methylprednisolone inhibits production of interleukin-1beta and interleukin-6 in the spinal cord following compression injury in rats. Journal of neurosurgical anesthesiology. 17(2): 82-5, 2005.
  • Newcomb, JD.Brown, WD.Rodriguez, AI.Garbuzova-Davis, S.Saporta, S.Sanberg, PR.Willing, AE. Behavioral alterations in Lewis rats following two-day continuous 3-nitropropionic acid administration. Neurotoxicity research. 8(3-4): 259-66, 2005.
  • Shamekh, R.Newcomb, J.Mallery, J.Cassady, CJ.Saporta, S.Cameron, DF.Sanberg, PR.Willing, AE. Survival of rat or mouse ventral mesencephalon neurons after cotransplantation with rat sertoli cells in the mouse striatum. Cell transplantation. 14(8): 551-64, 2005.
  • Sanberg, PR.Willing, AE.Garbuzova-Davis, S.Saporta, S.Liu, G.Sanberg, CD.Bickford, PC.Klasko, SK.El-Badri, NS. Umbilical cord blood-derived stem cells and brain repair. Annals of the New York Academy of Sciences. 1049(): 67-83, 2005.
  • Pollock, G.Pennypacker, KR.Mémet, S.Israël, A.Saporta, S. Activation of NF-kappaB in the mouse spinal cord following sciatic nerve transection. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. 165(4): 470-7, 2005.
  • Garbuzova-Davis, S.Gografe, SJ.Sanberg, CD.Willing, AE.Saporta, S.Cameron, DF.Desjarlais, T.Daily, J.Kuzmin-Nichols, N.Chamizo, W.Klasko, SK.Sanberg, PR. Maternal transplantation of human umbilical cord blood cells provides prenatal therapy in Sanfilippo type B mouse model. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 20(3): 485-7, 2006.
  • Shamekh, R.Cameron, DF.Willing, AE.Saporta, S. The role of connexins in the differentiation of NT2 cells in Sertoli-NT2 cell tissue constructs grown in the rotating wall bioreactor. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. 170(2): 277-84, 2006.
  • Garbuzova-Davis, S.Willing, AE.Saporta, S.Justen, EB.Misiuta, IE.Dellis, J.Sanberg, PR. Multiple transplants of hNT cells into the spinal cord of SOD1 mouse model of familial amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. 7(4): 221-6, 2006.
  • Malone, JI.Hanna, SK.Saporta, S. Hyperglycemic brain injury in the rat. Brain research. 1076(1): 9-15, 2006.
  • Shamekh, R.Mallery, J.Newcomb, J.Hushen, J.Saporta, S.Cameron, DF.Sanberg, CD.Sanberg, PR.Willing, AE. Enhancing tyrosine hydroxylase expression and survival of fetal ventral mesencephalon neurons with rat or porcine Sertoli cells in vitro. Brain research. 1096(1): 1-10, 2006.
  • El-Badri, NS.Hakki, A.Saporta, S.Liang, X.Madhusodanan, S.Willing, AE.Sanberg, CD.Sanberg, PR. Cord blood mesenchymal stem cells: Potential use in neurological disorders. Stem cells and development. 15(4): 497-506, 2006.
  • Garbuzova-Davis, S.Willing, AE.Saporta, S.Bickford, PC.Gemma, C.Chen, N.Sanberg, CD.Klasko, SK.Borlongan, CV.Sanberg, PR. Novel cell therapy approaches for brain repair. Progress in brain research. 157(): 207-22, 2006.
  • Misiuta, IE.Saporta, S.Sanberg, PR.Zigova, T.Willing, AE. Influence of retinoic acid and lithium on proliferation and dopaminergic potential of human NT2 cells. Journal of neuroscience research. 83(4): 668-79, 2006.
  • Shamekh, R.El-Badri, NS.Saporta, S.Pascual, C.Sanberg, PR.Cameron, DF. Sertoli cells induce systemic donor-specific tolerance in xenogenic transplantation model. Cell transplantation. 15(1): 45-53, 2006.
  • Garbuzova-Davis, S.Haller, E.Saporta, S.Kolomey, I.Nicosia, SV.Sanberg, PR. Ultrastructure of blood-brain barrier and blood-spinal cord barrier in SOD1 mice modeling ALS. Brain research. 1157(): 126-37, 2007.
  • Garbuzova-Davis, S.Saporta, S.Haller, E.Kolomey, I.Bennett, SP.Potter, H.Sanberg, PR. Evidence of Compromised Blood-Spinal Cord Barrier in Early and Late Symptomatic SOD1 Mice Modeling ALS. PLoS ONE. 2(11): e1205, 2007.
  • Newcomb, JD.Janowski, M.Zigova, T.Saporta, S.McGrogan, MP.Sanberg, PR.Willing, AE. A comparison of dopaminergic cells from the human NTera2/D1 cell line transplanted into the hemiparkinsonian rat. Life sciences. 81(6): 441-8, 2007.
  • Garbuzova-Davis, S.Saporta, S.Sanberg, PR. Implications of blood-brain barrier disruption in ALS. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. (): 1-2, 2008.
  • Shamekh, R.Saporta, S.Cameron, DF.Willing, AE.Sanberg, CD.Johe, K.Sanberg, PR. Effects of Sertoli cell-conditioned medium on ventral midbrain neural stem cells: a preliminary report. Neurotoxicity research. 13(3-4): 241-246, 2008.
  • Willing, AE.Garbuzova-Davis, S.Sanberg, PR.Saporta, S. Routes of stem cell administration in the adult rodent. Methods in molecular biology (Clifton, N.J.). 438(): 383-401, 2008.
  • Jiang, L.Newman, M.Saporta, S.Chen, N.Sanberg, C.Sanberg, PR.Willing, AE. MIP-1alpha and MCP-1 Induce Migration of Human Umbilical Cord Blood Cells in Models of Stroke. Current neurovascular research. 5(2): 118-24, 2008.
  • Jiang, L.Womble, T.Saporta, S.Chen, N.Sanberg, CD.Sanberg, PR.Willing, AE. Human umbilical cord blood cells decrease microglial survival in vitro. Stem cells and development. 19(2): 221-8, 2010.
  • Jiang, L.Saporta, S.Chen, N.Sanberg, CD.Sanberg, P.Willing, A. The effect of human umbilical cord blood cells on survival and cytokine production by post-ischemic astrocytes in vitro. Stem cell reviews. 6(4): 523-31, 2010.

    • Positions Held
  • Professor (Department of Pathology and Cell Biology, College of Medicine, University of South Florida 2006 - Present)
  • Graduate Faculty (College of Medicine, University of South Florida 2006 - Present)
  • Director (Scholarly Concentration in Research, College of Medicine, University of South Florida 2006 - Present)
  • Research Faculty (University of South Florida Diabetes Center, University of South Florida 2004 - Present)
  • Professor (Department of Neurological Surgery, College of Medicine, University of South Florida 2000 - Present)
  • Director (Anatomy Masters Program, College of Medicine, University of South Florida 2004 - 2011)


    • Memberships
  • American Society for Neural Therapy and Repair (Member, 2008 - Present)
  • American Association for the Advancement of Science (Member, 2008 - Present)
  • Cajal Club (Member, 1995 - Present)
  • Tampa Bay Area Chapter of the Society for Neuroscience (Member, 1983 - Present)
  • International Brain Research Organization (IBRO) (Member, 1977 - Present)
  • Society for Neuroscience (Member, 1975 - Present)
  • American Association of Anatomists (Member, 1975 - Present)


    • Awards/Honors
  • Outstanding Teaching Award (University of South Florida College of Medicine - 2011)
    		•
  • President (University of South Florida, College of Medicine Faculty - 2008)
    		•
  • Vice-President (University of South Florida, College of Medicine Faculty - 2007)
    		•
  • USF Health Leadership Institute  Charter Class (University of South Florida, College of Medicine - 2006)
    		•
  • Robert J. Grasso Award for Outstanding Dedication to Graduate Education (University of South Florida College of Medicine - 2006)
    		•


    Patents & Licensing
  • Sertoli Cells as Biochambers (US Patent No. 6,790,441. - 2004)
  • Method and Media for Enhancing Cryopreservation of Cells (US Patent No. 6,037,175. - 2000)
  • Method and Media for Enhancing Viability, Maturation, and Cryopreservation of Cells (US Patent No. 5,942,437. - 1999)


    • Grants
  • CREATION AND TRANSPLANTATION OF IMMUNOPRIVILEGED SERTOLI-NEURON-AGGREGATED CELLS (SNACS) FOR THE TREATMENT OF PARKINSON'S DISEASE ($232,000.00, 08/01/2001-09/30/2004)
  • CREATION AND TRANSPLANTATION OF IMMUNOPRIVILEGED SERTOLI-NEURON-AGGREGATED CELLS (SNACS) FOR THE TREATMENT OF PARKINSON'S DISEASE ($191,200.00, 08/01/2001-09/30/2004)
  • CREATION AND TRANSPLANTATION OF IMMUNOPRIVILEGED SERTOLI-NEURON-AGGREGATED CELLS (SNACS) FOR THE TREATMENT OF PARKINSON'S DISEASE ($47,800.00, 08/01/2001-09/30/2004)
  • CREATION AND TRANSPLANTATION OF IMMUNOPRIVILEGED SERTOLI-NEURON-AGGREGATED CELLS (SNACS) FOR THE TREATMENT OF PARKINSON'S DISEASE ($68,000.00, 08/01/2001-09/30/2004)
  • CREATION AND TRANSPLANTATION OF IMMUNOPRIVILEGED SERTOLI-NEURON-AGGREGATED CELLS (SNACS) FOR THE TREATMENT OF PARKINSON'S DISEASE ($124,850.00, 08/01/2001-09/30/2004)
  • CREATION AND TRANSPLANTATION OF IMMUNOPRIVILEGED SERTOLI-NEURON-AGGREGATED CELLS (SNACS) FOR THE TREATMENT OF PARKINSON'S DISEASE ($68,100.00, 08/01/2001-09/30/2004)
  • CREATION AND TRANSPLANTATION OF IMMUNOPRIVILEGED SERTOLI-NEURON-AGGREGATED CELLS (SNACS) FOR THE TREATMENT OF PARKINSON'S DISEASE ($34,050.00, 08/01/2001-09/30/2004)
  • SPINAL CORD REPAIR WITH HUMAN UMBILICAL CORD BLOOD CELLS ($66,805.00, 09/25/2003-06/30/2004)


    • Lectures
  • "Reach Out and Touch Someone: Differentiation of the Ntera2/D1Teratocarcinoma Cell Line to Neurons. " Grand Rounds, Department of Neurology. NC, United States - 2008.
  • "Stem Cell Therapies for Spinal Cord Injury" Plenary Lecture, IV International Aorta Conference. Brazil - 2008.
  • "Sertoli Cells and Neurodegenerative Disease: Can Sertoli Cells Protect Neurons?" Grand Rounds, Department of Internal Medicine. University of Perugia . Italy - 2007.
  • "Differentiation of Neural Precursor and Stem Cells: It Takes a Village to Differentiate a Neuron." Rhode Island Biomedical Research Infrastructure Network, University of Rhode Island. RI, United States - 2003.

    • Profile last modified on 06/09/2011